Caffeine vs. creatine: The influence on cognitive and physical performances

In a recent Nutrient study, researchers investigated the individual and combined effects of caffeine and creatine nitrate on cognitive and exercise performance in resistance-trained athletes. While caffeine enhances strength, endurance, and anaerobic performance, creatine boosts short-term power output during exercise. However, their interactions remain unclear.

The double-blinded, randomized trial involved 12 male athletes receiving high-dose caffeine, creatine nitrate, or a combination. Results showed that the combination notably improved cognitive function, especially in interference tests, but had minimal effects on short-term exercise performance. The study underscores the need for further research to understand the complex interaction between caffeine and creatine and their combined effects on cognitive and athletic performance. Additionally, longitudinal studies involving diverse populations, including female athletes, are necessary to broaden the findings and explore potential long-term effects.