New Research Links Aortic Valve Size to Calcification in Severe Aortic Stenosis

Recent research from Karl Landsteiner University of Health Sciences (KL Krems) challenges traditional diagnostic approaches to severe aortic stenosis (AS) by showing that aortic valve size, rather than sex, is a key factor in determining aortic valve calcification (AVC) levels.

Key Findings

• Valve size significantly influences AVC, independent of sex.
• Misclassification risk: Patients with smaller valves were more likely to have severe AS despite low AVC scores, leading to potential underdiagnosis.
• Call for revised diagnostic criteria: Incorporating valve size into diagnostic thresholds may improve accuracy and ensure timely treatment.

The study analyzed 601 patients using cardiac CT scans and emphasizes the need for personalized diagnostic standards. Conducted in collaboration with leading Austrian medical institutions, these findings could shape future clinical guidelines and enhance patient outcomes in AS diagnosis and treatment.

17-03-2025

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