A new study presented at ENDO 2025 reveals that intermittent energy restriction (IER), followed just two days per week, may offer greater benefits for individuals with obesity and type 2 diabetes than other diet strategies. Researchers from The First Affiliated Hospital of Zhengzhou University compared three dietary approaches—IER, time-restricted eating (TRE), and continuous energy restriction (CER)—in a 16-week randomized clinical trial involving 90 patients. While all groups showed similar improvements in HbA1c and weight loss, the IER group achieved better results in reducing fasting blood glucose, improving insulin sensitivity, and lowering triglycerides. Adherence was also highest in the IER group (85%), suggesting better long-term feasibility. No serious adverse events occurred. According to lead researcher Dr. Haohao Zhang, these findings provide important clinical guidance for dietary planning in managing diabetes and obesity, emphasizing IER as a practical and effective approach.
23-07-2025