Researchers from the University of Chicago have discovered that zeaxanthin, a nutrient best known for protecting vision, can also strengthen the immune system’s ability to fight cancer. Published in Cell Reports Medicine, the study found that zeaxanthin enhances the activity of CD8+ T cells, immune cells responsible for killing tumor cells. The compound stabilizes T-cell receptors, triggering stronger signaling and improved tumor-killing responses. In mouse models, zeaxanthin supplementation slowed tumor growth and amplified the effects of immune checkpoint inhibitors, a major form of cancer immunotherapy. Tests on human T cells also showed enhanced ability to destroy melanoma, multiple myeloma, and glioblastoma cells. Because zeaxanthin is safe, affordable, and naturally present in foods like spinach and orange peppers, researchers believe it could serve as an accessible immunotherapy enhancer. Further clinical trials are needed to confirm whether it can safely and effectively improve cancer treatment outcomes in patients.
06-10-2025