Neonicotinoid Pesticides and Male Reproductive Risks

A new review of studies from 2005–2025 links neonicotinoid pesticides—the world’s most widely used insecticides—to male reproductive toxicity in lab animals. Over two-thirds of the 21 studies examined found reduced sperm count, poor motility, abnormal sperm shape, hormonal disruption, and testicular damage. Higher doses or long-term exposure caused more severe or lasting harm.

Imidacloprid showed the most widespread testicular injury and DNA damage, while acetamiprid and clothianidin impaired hormone regulation, weakened antioxidant defenses, and lowered sperm concentration. Even at low doses, thiacloprid led to major drops in sperm viability.

Neonics are systemic pesticides that spread throughout plants and are now found in food, water, wildlife, and human tissues. Limited human studies suggest links to delayed puberty, lower testosterone, and reduced sperm motility.

Researchers call for stronger safety testing, evaluation of pesticide mixtures, and greater scrutiny of long-term exposure to protect reproductive health.

15-11-2025