High Tyrosine Levels Linked to Shorter Lifespan in Men

A recent study published in Aging-US suggests that elevated levels of the amino acid tyrosine may be associated with a shorter lifespan in men. Researchers from the University of Hong Kong and the University of Georgia analyzed health and genetic data from more than 270,000 participants in the UK Biobank to explore how two amino acids—phenylalanine and tyrosine—affect longevity.

Initial observations linked both amino acids to a higher mortality risk, but deeper genetic analysis revealed that only tyrosine showed a consistent connection to reduced life expectancy in men. According to the findings, men with higher tyrosine levels could live nearly a year less on average. No significant association was found in women.

Tyrosine plays a key role in producing neurotransmitters such as dopamine, which influence mood and brain function. Scientists believe its effects on metabolism, insulin resistance, or hormone signaling may partly explain the gender-specific results.

06-03-2026