Fish Oil Supplements May Not Protect Everyone From Colon Cancer

Omega-3 supplements are widely used for their anti-inflammatory benefits, but new research suggests their cancer-protective effects may depend on a specific enzyme. Scientists from the University of Michigan and University of Texas MD Anderson Cancer Center found that an enzyme called ALOX15 plays a key role in determining whether fish oil helps suppress colorectal tumors.

The study, published in Cellular and Molecular Gastroenterology and Hepatology, showed that without ALOX15, omega-3 fatty acids — particularly DHA — could lose their anti-inflammatory effects and potentially promote tumor growth in mice. EPA appeared more protective, especially in forms such as those found in Lovaza.

Researchers say not all fish oil supplements work the same way, and individual biology may influence outcomes. Patients are encouraged to consult healthcare professionals before using omega-3 supplements for cancer prevention.

13-02-2026