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Following the MIND diet may be associated with slower changes in brain structure as people age, according to a long-term study published in the Journal of Neurology, Neurosurgery & Psychiatry.
Researchers examined 1,647 middle-aged and older adults from the Framingham Heart Study Offspring cohort. Participants underwent repeated health assessments and brain MRI scans over several years, while their eating habits were evaluated through food-frequency questionnaires. The researchers then compared dietary patterns with changes in brain structure over time.
The MIND diet combines elements of the Mediterranean and DASH dietary approaches. It places emphasis on green leafy vegetables, other vegetables, berries, nuts, whole grains, fish, beans, olive oil and poultry. It also recommends limiting foods such as red meat, sweets, pastries and fried fast food.
During an average follow-up period of about 12 years, participants with higher MIND diet scores experienced slower loss of grey matter. The researchers reported that every three-point increase in the diet score was associated with approximately 20% less age-related grey-matter decline, a difference they described as equivalent to about 2.5 years of delayed brain ageing.
Some individual foods showed particularly notable associations. Higher berry and poultry consumption was linked with healthier changes in certain brain structures, while greater intake of sweets and fried fast foods was associated with less favourable changes.
The study also produced some unexpected findings, including associations between higher whole-grain intake and certain unfavourable structural changes. The researchers cautioned that these results require further investigation.
Importantly, the study was observational and therefore cannot establish that the MIND diet directly caused the slower brain changes. Dietary information was also based partly on participants' reported food intake, which can introduce recall errors.
01-10-2026