Prenatal Glyphosate Exposure Linked to Multi-Generational Health Effects

A new study in Science of the Total Environment found that prenatal exposure to low levels of glyphosate, the world’s most widely used herbicide, caused metabolic and behavioral disruptions across two generations of mice. Offspring from exposed mothers showed glucose intolerance, insulin resistance, reduced GLP-1 levels, and gut barrier damage. Both generations also exhibited impaired memory and reduced locomotion.

Notably, these adverse effects occurred at exposure levels comparable to Americans’ average dietary intake and well below the U.S. Environmental Protection Agency’s (EPA) “safe” limits.

Researchers warned that even doses previously deemed harmless can cause lasting physiological changes across generations. Given that glyphosate-based products such as Roundup® are widely present in food, water, and dust, the study underscores an urgent need to reassess regulatory thresholds to better protect public health from long-term, low-level pesticide exposure.

02-11-2025